Ukusetshenziswa kwe-Hydroxy Methionine Copper 1

Izinhlelo Zokusebenza Zomkhiqizo

1) Ama-broiler

Uma ama-MMHAC (ama-chelate e-hydroxy methionine ethusi, i-zinc, kanye ne-manganese) zengezwe ekudleni kwenkukhu, imiphumela ibonise ukuthi—uma kuqhathaniswa namaminerali ajwayelekile angaphili—ukufakwa kwe-MMHAC kwandisa kakhulu isisindo somzimba kanye nesisindo semisipha ye-drumstick (ithanga), kwathuthukisa ukugayeka kwethusi, futhi akuzange kube nemiphumela emibi empilweni ye-gizzard noma yethambo.

Ithebula 1. Isisindo sokucubungula izidumbu (g/inyoni) kanye nesifuba esinokhuni kanye nesifuba esimhlophe esinama-striping scores ezinkukhu eziphakelwa i-inorganic kanye ne-methionine hydroxyl analogue chelated zinc, ithusi, kanye ne-manganese ukwelashwa kokudla sat usuku lwama-42.

Into	I-ITM	M10	T125	I-M30	I-SEM	Inani le-P
Isifuba	684	716	719	713	14.86	0.415
Ithanga	397	413	412	425	7.29	0.078
Induku Yesigubhu	320	335	332	340	4.68	0.058
Ithanga kanye nenduku yesigubhu	717 a	748 ab	745 ab	765 b	11.32	0.050
Iphedi yamafutha	32.3	33.1	33.4	35.5	1.59	0.546
Isibindi	68.0	67.4	66.0	71.1	2.41	0.528
Inhliziyo	18.8	18.6	19.2	19.2	0.68	0.898
Izinso	9.49	10.2	10.6	10.6	0.51	0.413

Qaphela: ITM: Amaminerali angabonakali 110 ppm Zn as ZnSO4 16 ppm Cu as CuSO4 kanye no-120 ppm Mn as MnO per Ross 308 izincomo zokudla okunempilo;

I-M10: Amanani angu-40 ppm Zn 10 ppm Cu kanye no-40 ppm Mn njenge-chelate;

I-T125: Amaminerali angabonakali angu-110 ppm Zn njenge-ZnSO4 kanye no-120 ppm Mn njenge-MnO ngokweziqondiso ze-Ross 308 ezine-125 ppm Cu njenge-tribasic copper chloride (TBCC);

I-M30 = 40 ppm Zn, 30 ppm Cu, kanye ne-40 ppm Mn njenge-chelate. Amanani emgqeni ofanayo anemibhalo engenhla ehlukene ahluka kakhulu (P < 0.05).

2) Izingulube

Ucwaningo luhlole imiphumela yokushintsha kancane amaminerali angabonakali nge-mineral methionine hydroxy analogue chelates (MMHAC) ekudleni kwezingulube zombili kanye nezingulube zazo ezincane. Imiphumela ibonise ukuthi ukwengezwa kwe-MMHAC kunciphisa ukwehla kwesisindo somzimba ezingulubeni ezincelisayo, kwakhuthaza ukukhuphuka kwesisindo somzimba wezingulube ezincane ngosuku lwe-18, kwathuthukisa kakhulu amazinga e-acetylation yemisipha yamathambo lapho kuzalwa, futhi kwanciphisa ukubonakaliswa kwezakhi zofuzo eziningi ezihlobene nokuvuvukala kanye nokukhula kwemisipha. Sekukonke, i-MMHAC ithuthukise impilo yamathumbu kanye nokukhula kwemisipha ezingulubeni ezincane ngokusebenzisa umthethonqubo we-epigenetic kanye nokuthuthukiswa, okuthuthukisa amandla azo okukhula.

Ithebula 2 Imiphumela eyengeziwe ye-mineral methionine hydroxy analogue chelate ekudleni kwengulube ekubonakalisweni kwe-mRNA ebalulekile ehlobene nokuvuvukala kwe-jejunal engulubeni encelayo

Into	I-ITM	I-CTM	I-SEM	P- inani
d 1 yokuncelisa x 10^-5
IL-8	1344	1018	178	0.193
I-MUC2	5380	5511	984	0.925
I-NF-κB (ikhasi 50)	701	693	93	0.944
I-NF-κB (ikhasi 105)	1991	1646	211	0.274
I-TGF-b1	Kusukela ngo-1991	1600	370	0.500
I-TNF-α	11	7	2	0.174
d 18 yokuncelisa x 10^-5
IL-8	1134	787	220	0.262
I-MUC2	5773	3871	722	0.077

Qaphela: I-Interleukin-8 (IL-8), i-mucin-2 (MUC2), i-nuclear factor-κB (NF-κB), i-transforming growth factor-1 (TGF-1), kanye ne-tumor necrosis factor-α (TNF-α)

I-ITM = imithombo evamile yezamaminerali angabonakali (izinga lokufakwa kwe-0.2% ekudleni)

I-CTM = 50:50 amaminerali i-methionine hydroxy analogue chelate kanye namaminerali angaphili (izinga lokufakwa elingu-0.2% ekudleni)

3)Izilwane ezidla inyama

Ekunceliseni izinkomo zobisi, kufakwa esikhundleni sengxenye ye-copper sulfateithusi le-hydroxy methioninekwandise kakhulu ukuhlushwa kwe-plasma copper, kwathuthukisa ukugayeka kwe-neutral detergent fiber (NDF) kanye ne-acid detergent fiber (ADF), futhi kwathuthukisa kokubili isivuno sobisi kanye nokukhiqizwa kobisi olulungisiwe ngamafutha ngo-4%. Lokhu okutholakele kubonisa ukuthi ukufaka esikhundleni se-copper sulfate nge-(HMTBA)₂-Cu kancane ekudleni kwezinkomo zobisi kuyindlela yokudla ephumelela kakhulu.

Ithebula 3 Imiphumela ye-methionine hydroxy Cu [(HMTBA)2-Cu] ekwakhiweni kobisi lwezinkomo

Into	S	SM	M	I-SEM	Inani le-P
I-DMI, kg/ngosuku	19.2	20.3	19.8	0.35	0.23
Isivuno sobisi, kg/ngosuku	28.8	33.8	31.3	1.06	0.08
Amafutha, %	3.81	3.74	3.75	0.06	0.81
Amaprotheni, %	3.34	3.28	3.28	0.04	0.19
I-Lactose, %	4.48	4.35	4.43	0.05	0.08
I-SNF, %	8.63	8.84	8.63	0.05	0.33
Isivuno samafutha, kg/ngosuku	1.04	1.22	1.10	0.04	0.09
Isivuno samaprotheni, kg/ngosuku	0.92	0.92	0.90	0.03	0.72
Isivuno se-lactose, kg/ngosuku	1.23	1.23	1.21	0.04	0.45
I-Urea N, mg/dL	18.39	17.70	18.83	0.45	0.19
4% FCM, kg/ngosuku	26.1	30.1	27.5	0.91	0.06

Ukwelashwa: S = Cu sulfate kuphela: 12 mg we-Cu ohlinzekwa yi-CuSO4 ngekhilogramu ngayinye yokugxila; SM = Cu sulfate kanye (HMTBA)2-Cu: 6 mg we-Cu ohlinzekwa yi-CuSO4, kanye nomunye u-6 mg we-Cu ohlinzekwa yi-(HMTBA)2-Cu ngekhilogramu ngayinye yokugxila; M = (HMTBA)2-Cu kuphela: 12 mg we-Cu ohlinzekwa yi-(HMTBA)2-Cu ngekhilogramu ngayinye yokugxila.