Ngomongo wenhloso “yekhabhoni embaxambili” kanye noguquko oluluhlaza embonini yokufuywa kwezilwane emhlabeni wonke, ubuchwepheshe be-peptide trace element encane sebuphenduke ithuluzi eliwumgogodla lokuxazulula ukungqubuzana okumbaxambili “kokuthuthukisa ikhwalithi nokusebenza kahle” kanye “nokuvikelwa kwemvelo” embonini ngezici zayo ezisebenzayo zokumunca kanye nezici zokunciphisa ukungcola. Ngokusetshenziswa kwe-EU "Co-additive Regulation (2024 / EC)" kanye nokuthandwa kobuchwepheshe be-blockchain, insimu ye-organic micro-minerals ibhekene nokuguqulwa okujulile kusukela ekubunjweni okunamandla kuya kumamodeli esayensi, futhi kusukela ekuphathweni okubanzi kuya ekulandeleleni okugcwele. Lesi sihloko sihlaziya ngokuhlelekile inani lesicelo sobuchwepheshe be-peptide encane, sihlanganisa isiqondiso senqubomgomo yokufuywa kwezilwane, izinguquko ezifunwayo zemakethe, ukuphumelela kobuchwepheshe bama-peptide amancane, nezidingo zekhwalithi, kanye nezinye izitayela ezihamba phambili, futhi iphakamisa indlela yokuguqulwa eluhlaza ekufuyweni kwezilwane ngo-2025.
1. Izinkambiso zenqubomgomo
1) I-EU iqalise ngokusemthethweni uMthetho Wokunciphisa Ukukhishwa Kwemfuyo ngoJanuwari 2025, odinga ukuncishiswa ngo-30% kwezinsalela zensimbi esindayo ekuphakeleni , kanye nokusheshisa ukushintshela kwemboni kuma-organic trace elements. I-Green Feed Act ka-2025 idinga ngokusobala ukuthi ukusetshenziswa kwezinto ezilandelwayo ezingaphili (njenge-zinc sulfate ne-copper sulfate) ekuphakeleni kwehliswe ngo-50% ngo-2030, nokuthi imikhiqizo ye-organic chelated ithuthukiswe njengento ebaluleke kakhulu.
2) UMnyango Wezolimo Nezindaba Zasemakhaya waseShayina ukhiphe “Ikhathalogi Yokufinyelela Okuhlaza Kwezithako Zokudla”, futhi imikhiqizo emincane ye-peptide chelated yafakwa ohlwini “njengezinye izindlela ezinconyiwe” okokuqala ngqa.
3) INingizimu-mpumalanga ye-Asia: Amazwe amaningi asungule ngokuhlanganyela “Uhlelo Lokulima Lokulwa Nemithi Elwa Namagciwane” ukuze kuthuthukiswe izakhi zokulandelela ukusuka “ekwengezeni ukudla okunomsoco” kuya “ekulawuleni okusebenzayo” (okufana nokulwa nokucindezeleka nokuthuthukiswa kwamasosha omzimba).
2. Izinguquko ekudingeni izimakethe
Ukwanda kwesidingo sabathengi “senyama enezinsalela zemithi elwa namagciwane” kuqhubekisele phambili isidingo sezinto zokulandela ezihambisana nemvelo ezinamazinga aphezulu okumuncwa ngasohlangothini lokulima. Ngokwezibalo zomkhakha, usayizi wemakethe yomhlaba wonke yezinto ezincane ze-peptide chelated trace inyuke ngo-42% unyaka nonyaka ku-Q1 2025.
Ngenxa yesimo sezulu esibi kakhulu eNyakatho Melika naseNingizimu-mpumalanga ye-Asia, amapulazi anaka kakhulu indima ye-trace elements ekumelaneni nengcindezi kanye nokuthuthukisa ukuvikeleka kwezilwane.
3. Ukuphumelela kwezobuchwepheshe: ukuncintisana okuyinhloko kwemikhiqizo emincane ye-peptide chelated trace
1) I-bioavailability ephumelelayo, ukweqa ibhodlela lokumuncwa kwendabuko
Ama-peptide amancane ama-chelate alandelela izakhi ngokusonga ama-ion ensimbi ngamaketanga e-peptide ukuze akhe izakhiwo ezizinzile, ezimuncwa ngenkuthalo ngohlelo lokuthutha lwe-peptide yamathumbu (njenge-PepT1), igwema ukulimala kwe-asidi yesisu kanye nokuphikiswa kwe-ion, futhi i-bioavailability yawo iphakeme izikhathi ezi-2-3 kunosawoti we-inorganic.
2) I-synergy esebenzayo yokuthuthukisa ukusebenza kokukhiqiza ngezilinganiso eziningi
Izakhi zokulandelela ze-peptide ezincane zilawula izitshalo zamathumbu (amagciwane e-lactic acid akhula izikhathi ezingu-20-40), athuthukise ukuthuthukiswa kwezitho zokuzivikela (i-antibody titer ikhuphuka izikhathi ezingu-1.5), futhi athuthukise ukumuncwa kwezakhi (isilinganiso sokuphakelayo kuya kwenyama sifinyelela ku-2.35: 1), ngaleyo ndlela sithuthukise ukusebenza kokukhiqiza ngezilinganiso eziningi (+ 48%) kanye nokukhiqizwa kweqanda nsuku zonke.
3) Ukuzinza okuqinile, kuvikela ngempumelelo ikhwalithi yokuphakelayo
Ama-peptide amancane enza ukuxhumana okunamazinyo amaningi nama-ion ensimbi ngokusebenzisa i-amino, i-carboxyl namanye amaqembu asebenzayo ukuze akhe uhlaka lwe-chelate lwendandatho enamalungu amahlanu/amalungu ayisithupha. Ukuxhumana kwendandatho kunciphisa amandla esistimu, isithiyo esibulalayo sivikela ukuphazamiseka kwangaphandle, futhi ukungathathi hlangothi kweshaji kunciphisa ukuxoshwa kwe-electrostatic, okuhlanganisa kuthuthukisa ukuzinza kwe-chelate.
| Ukuzinza kwama-ligand ahlukene abophezela kuma-ion ethusi ngaphansi kwezimo ezifanayo zomzimba | |
| Ukuzinza kwe-Ligand 1,2 | Ukuzinza kwe-Ligand 1,2 |
| I-Log10K[ML] | I-Log10K[ML] |
| Ama-Amino Acids | I-Tripeptide |
| I-Glycine 8.20 | I-Glycine-Glycine-Glycine 5.13 |
| I-Lysine 7.65 | I-Glycine-Glycine-Histidine 7.55 |
| I-Methionine 7.85 | I-Glycine Histidine Glycine 9.25 |
| I-Histidine 10.6 | I-Glycine Histidine Lysine 16.44 |
| I-Aspartic acid 8.57 | I-Gly-Gly-Tyr 10.01 |
| I-Dipeptide | I-Tetrapeptide |
| I-Glycine-Glycine 5.62 | I-Phenylalanine-Alanine-Alanine-Lysine 9.55 |
| I-Glycine-Lysine 11.6 | I-Alanine-Glycine-Glycine-Histidine 8.43 |
| I-Tyrosine-Lysine 13.42 | I-Quote: 1.Ukuzinza Kokuhlala Ukunquma Nokusetshenziswa, uPeter Gans. 2.Izinzalo ezikhethwe ngokucijile zezakhiwo zensimbi,Isizindalwazi se-NIST 46. |
| I-Histidine-methionine 8.55 | |
| I-Alanine-Lysine 12.13 | |
| I-Histidine-serine 8.54 | |
Fig 1 Ukuzinza okungaguquki kwama-ligand ahlukene abopha ku-Cu2+
Imithombo yamaminerali eboshelwe ngobuthaka ingase ibe nokusabela kwe-redox ngamavithamini, uwoyela, ama-enzyme kanye nama-antioxidants, okuthinta inani elisebenzayo lezakhi zokudla. Kodwa-ke, lo mphumela ungancishiswa ngokukhetha ngokucophelela i-trace element enokuqina okuphezulu nokusabela okuphansi ngamavithamini.
Ukuthatha amavithamini njengesibonelo, Concarr et al. ( 2021a ) ufunde ukuzinza kwe-vitamin E ngemuva kokugcinwa kwesikhashana kwe-inorganic sulfate noma izinhlobo ezahlukene ze-organic mineral premixes. Ababhali bathola ukuthi umthombo wezakhi zokulandelela wawuthinta kakhulu ukuzinza kwe-vitamin E, futhi i-premix esebenzisa i-organic glycinate yayinokulahlekelwa kwevithamini okuphezulu kakhulu kwe-31.9%, kulandelwa i-premix esebenzisa ama-amino acid complexes, okwakungu-25.7%. Awukho umehluko obalulekile ekulahlekeni kokuzinza kukavithamini E ku-premix equkethe usawoti wamaprotheni uma kuqhathaniswa neqembu lokulawula.
Ngokufanayo, izinga lokugcinwa kwamavithamini ku-organic trace element chelates ngendlela yama-peptide amancane (okuthiwa i-x-peptide multi-minerals) iphakeme kakhulu kuneminye imithombo yamaminerali (Umfanekiso 2). (Qaphela: I-organic multi-minerals ku-Figure 2 iwuchungechunge lwe-glycine multi-mineral).
Umdwebo 2 Umphumela wama-premixes avela emithonjeni ehlukene ngezinga lokugcinwa kwamavithamini
I-1) Ukunciphisa ukungcola kanye negesi eliphumayo ukuze kuxazululwe izinkinga zokulawulwa kwemvelo
4. Izidingo zekhwalithi: ukumisa nokuhambisana: ukubamba indawo ephakeme yokuncintisana kwamanye amazwe
1) Ukujwayela imithetho emisha ye-EU: ukuhlangabezana nezidingo zemithetho ye-2024/EC futhi unikeze amamephu wendlela ye-metabolic
2) Yakha izinkomba eziphoqelekile kanye nezinga le-chelation elebula, ukuhlukana okungaguquki, kanye nemingcele yokuzinza kwamathumbu
I-3) Thuthukisa ubuchwepheshe bokugcina ubufakazi be-blockchain, imingcele yenqubo yokulayisha kanye nemibiko yokuhlola kuyo yonke inqubo
Ubuchwepheshe be-peptide trace element encane akuwona nje uguquko ezithasiselweni zokudla, kodwa futhi injini eyinhloko yokuguqulwa okuluhlaza embonini yemfuyo. Ngo-2025, ngokusheshisa ukwenziwa kwedijithali, isikali kanye nokwenza amazwe ngamazwe, lobu buchwepheshe buzolungisa kabusha ukuncintisana kwemboni ngokusebenzisa izindlela ezintathu “zokuthuthukisa ukusebenza kahle-ukuvikelwa kwemvelo kanye nokunciphisa ukungcola-inani-kwengezwe”. Ngokuzayo, kuyadingeka ukuthi kuqhutshekwe nokuqinisa ukusebenzisana phakathi kwezimboni, izifundiswa nocwaningo, kugqugquzelwe ukuhwebelana kwamazinga ezobuchwepheshe emazweni ngamazwe, nokwenza isisombululo saseShayina sibe uphawu lokuthuthukiswa okusimeme kwemfuyo yomhlaba wonke.
Isikhathi sokuthumela: Apr-30-2025
