IHydroxy Methionine Copper MHA-Cu SUSTAR
Ulwazi Lomkhiqizo
Igama lomkhiqizo: I-Hydroxy Methionine Copper - Ibanga lokuphakelayo
Ifomula yemolekyuli: C₁₀H₁₈O₆S₂Cu
Isisindo se-molecule: 363.9
Inombolo ye-CAS: 292140-30-8
Ukubukeka: Impushana eluhlaza okwesibhakabhaka
Izakhiwo ze-Physicochemical
| Into | Inkomba |
| I-analogue ye-methionine hydroxy,% | ≥ 78.0% |
| Cu²⁺, % | ≥ 15.0% |
| I-Arsenic (kungaphansi kwe-As) mg/kg | ≤ 5.0 |
| I-Plumbum (kuncike ku-Pb) mg/kg | ≤ 10 |
| Okuqukethwe kwamanzi % | ≤ 5.0 |
| Ukulunga (425μm izinga lokuphasa (40 mesh)), % | ≥ 95.0 |
Ukusebenza Komkhiqizo
1. Ikhuthaza imisebenzi elwa namagciwane kanye ne-anti-inflammatory, ithuthukisa ukumelana nezifo.
2. Ithuthukisa i-iron metabolism kanye ne-hemoglobin synthesis, isiza ekuvimbeleni ukuntuleka kwegazi.
3. Ithuthukisa ukwakheka kwe-keratin, ithuthukise izinwele, uphaphe, nesimo sesikhumba.
4. Yandisa umsebenzi we-enzyme nokusebenza kahle kwamandla, ithuthukisa isilinganiso sokuguqulwa kokuphakelayo (FCR).
Izicelo Zomkhiqizo
1) Ama-broilers
Lapho i-MMHACs (i-hydroxy methionine chelates yethusi, i-zinc, ne-manganese) yengezwa ekudleni kwe-broiler, imiphumela yabonisa ukuthi-uma kuqhathaniswa namaminerali endabuko e-inorganic trace-ukufakwa kwe-MMHACs kwandise kakhulu isisindo somzimba kanye ne-drumstick (ithanga) isisindo somzimba, ukuthuthukiswa kokugaya kwethusi, futhi akuzange kube nemiphumela emibi yethambo noma impilo.
Ithebula 1 .Isisindo sokucubungula isidumbu (g/inyoni) kanye nesifuba sokhuni nesifuba esinemigqa emhlophe yezinkukhu ezifunzwa i-inorganic kanye ne-methionine hydroxyl analogue chelated zinc, ithusi, kanye nokwelashwa kokudla kwe-manganese kwahlala usuku lwama-42.
| Into | I-ITM | M10 | T125 | M30 | I-SEM | P-Value |
| Isifuba | 684 | 716 | 719 | 713 | 14.86 | 0.415 |
| Ithanga | 397 | 413 | 412 | 425 | 7.29 | 0.078 |
| I-Drumstick | 320 | 335 | 332 | 340 | 4.68 | 0.058 |
| Ithanga nesigubhu | 717 a | 748b | 745ab | 765 b | 11.32 | 0.050 |
| Iphedi lamafutha | 32.3 | 33.1 | 33.4 | 35.5 | 1.59 | 0.546 |
| Isibindi | 68.0 | 67.4 | 66.0 | 71.1 | 2.41 | 0.528 |
| Inhliziyo | 18.8 | 18.6 | 19.2 | 19.2 | 0.68 | 0.898 |
| Izinso | 9.49 | 10.2 | 10.6 | 10.6 | 0.51 | 0.413 |
Qaphela: I-ITM: I-Inorganic trace mineral 110 ppm Zn njenge-ZnSO4 16 ppm Cu njenge-CuSO4 kanye ne-120 ppm Mn njenge-MnO ngezincomo zokudla okunomsoco kwe-Ross 308;
I-M10: Amanani angu-40 ppm Zn 10 ppm Cu kanye no-40 ppm Mn njenge-chelate;
T125: Inorganic trace mineral 110 ppm Zn as ZnSO4 and 120 ppm Mn as MnO per Ross 308 guidelines with 125 ppm Cu as tribasic copper chloride (TBCC);
M30 = 40 ppm Zn, 30 ppm Cu, kanye no-40 ppm Mn njenge-chelate. Amanani emugqeni ofanayo onemibhalo engenhla ehlukene ahluke kakhulu (P <0.05).
2) Izingulube
Ucwaningo luphenye imiphumela yokushintsha kancane amaminerali e-inorganic trace esikhundleni se-mineral methionine hydroxy analogue chelates (MMHAC) ekudleni kwezinsikazi kuzo zombili izingulube namazinyane azo. Imiphumela yabonisa ukuthi ukwesekwa kwe-MMHAC kunciphisa ukulahlekelwa kwesisindo somzimba ezingulubeni ezincelisayo, kwakhuthaza ukuzuza kwesisindo somzimba wengulube ngosuku lwe-18, kwathuthukisa kakhulu amazinga e-acetylation emisipha ye-skeletal histone ngesikhathi sokuzalwa, futhi kwehlisa ukubonakaliswa kwezakhi zofuzo ezihlobene nokuvuvukala nokuthuthukiswa kwemisipha. Sekukonke, i-MMHAC ithuthukise impilo yamathumbu kanye nokuthuthukiswa kwemisipha kumantshontsho engulube ngokusebenzisa ukulawulwa kwe-epigenetic kanye nokuthuthuka, ithuthukisa amandla azo okukhula.
Ithebula 2 Imiphumela eyengeziwe ye-mineral methionine hydroxy analogue chelate ekudleni kwezingulube ekuvezeni kwe-mRNA eyinhloko ehlobene nokuvuvukala kwe-jejunal ekunceliseni ingulube.
| Into
| I-ITM | I-CTM | I-SEM | P- inani |
| d 1 yokuncelisa x 10-5 | ||||
| I-IL-8 | 1344 | 1018 | 178 | 0.193 |
| I-MUC2 | 5380 | 5511 | 984 | 0.925 |
| I-NF-κB (p50) | 701 | 693 | 93 | 0.944 |
| I-NF-κB (p105) | 1991 | 1646 | 211 | 0.274 |
| I-TGF-b1 | Kusukela ngo-1991 | 1600 | 370 | 0.500 |
| I-TNF-α | 11 | 7 | 2 | 0.174 |
| d 18 wokuncelisa x 10-5 | ||||
| I-IL-8 | 1134 | 787 | 220 | 0.262 |
| I-MUC2 | 5773 | 3871 | 722 | 0.077 |
Qaphela:Interleukin-8 (IL-8), mucin-2 (MUC2), nuclear factor-κB (NF-κB), transforming growth factor-1 (TGF-1), and tumor necrosis factor-α (TNF-α)
I-ITM = imithombo evamile ye-inorganic of trace minerals (izinga le-0.2% lokufakwa ekudleni)
I-CTM = 50:50 i-mineral methionine hydroxy analogue chelate namaminerali angaphili (0.2% izinga lokufakwa ekudleni)
3)Ama-Ruminants
Ezinkomeni zobisi ezimunyisayo, ukushintsha ingxenye ye-copper sulfate nge-hydroxy methionine yethusi kwandise kakhulu ukugcwala kwe-plasma yethusi, kwathuthukisa ukugayeka kokudla kwe-neutral detergent fiber (NDF) kanye ne-acid detergent fiber (ADF), futhi kwathuthukisa kokubili ukukhiqizwa kobisi kanye no-4% wokukhiqizwa kobisi olulungiswe ngamafutha. Lokhu okutholakele kubonisa ukuthi ukufaka esikhundleni se-copper sulfate nge-(HMTBA)₂-Cu ekudleni kwenkomo yobisi kuyisu elisebenza kahle kakhulu lokudla okunempilo.
Ithebula 3 Imithelela ye-methionine hydroxy Cu [(HMTBA)2-Cu] ekwakhekeni kobisi lwezinkomo
| Into | S | SM | M | I-SEM | P-value |
| I-DMI, kg/d | 19.2 | 20.3 | 19.8 | 0.35 | 0.23 |
| Isivuno sobisi, kg/d | 28.8 | 33.8 | 31.3 | 1.06 | 0.08 |
| Amafutha, % | 3.81 | 3.74 | 3.75 | 0.06 | 0.81 |
| Amaprotheni, % | 3.34 | 3.28 | 3.28 | 0.04 | 0.19 |
| I-Lactose, % | 4.48 | 4.35 | 4.43 | 0.05 | 0.08 |
| I-SNF, % | 8.63 | 8.84 | 8.63 | 0.05 | 0.33 |
| Isivuno samafutha, kg/d | 1.04 | 1.22 | 1.10 | 0.04 | 0.09 |
| Isivuno samaprotheni, kg/d | 0.92 | 0.92 | 0.90 | 0.03 | 0.72 |
| Isivuno seLactose, kg/d | 1.23 | 1.23 | 1.21 | 0.04 | 0.45 |
| Urea N, mg/dL | 18.39 | 17.70 | 18.83 | 0.45 | 0.19 |
| 4% FCM, kg/d | 26.1 | 30.1 | 27.5 | 0.91 | 0.06 |
Ukwelashwa: S = Cu sulfate kuphela: 12 mg we-Cu ohlinzekwa yi-CuSO4 ngekhilogremu ngayinye yokugxila; SM = I-Cu sulfate kanye (HMTBA)2-Cu: 6 mg ye-Cu ehlinzekwa yi-CuSO4, kanye nomunye u-6 mg we-Cu ohlinzekwa yi-(HMTBA)2-Cu ngekhilogremu ngayinye yokugxilisa ingqondo; M = (HMTBA)2-Cu kuphela: 12 mg we-Cu ehlinzekwa yi-(HMTBA)2-Cu ikhilogremu ngayinye yokugxilisa ingqondo.
Ukusetshenziswa kanye Nesilinganiso
Izinhlobo ezisebenzayo: Izilwane ezifuywayo
Ukusetshenziswa nesikali: Izinga elinconyiwe lokufakwa ngethani ngalinye lokuphakelayo okuphelele liboniswa kuthebula elingezansi (iyunithi: g/t, ibalwa njenge-Cu²⁺).
| Ingulube yengulube | Ukukhulisa/Ukuqeda Ingulube | Izinkukhu | Izinkomo | Izimvu | Isilwane sasemanzini |
| 35-125 | 8-20 | 5-20 | 3-20 | 5-20 | 10-15 |
Ukucaciswa kwephakheji:25 kg/isikhwama, izikhwama ezinezingqimba ezimbili zangaphakathi nezangaphandle.
Isitoreji:Gcina kuvaliwe endaweni epholile, engenamoya, neyomile. Vikela kumswakama.
Impilo yeshelufu:Izinyanga ezingama-24.
Ukukhetha Okuphezulu kwe-International Grop
Iqembu le-Sustar linobambiswano lweminyaka eminingi ne-CP Group, i-Cargill, i-DSM, i-ADM, i-Deheus, i-Nutreco, i-New Hope, i-Haid, i-Tongwei kanye nenye inkampani ye-TOP 100 enkulu yokuphakelayo.
Ubukhulu Bethu
Uzakwethu Othembekile
Amakhono ocwaningo nentuthuko
Ukuhlanganisa amathalente eqembu ukwakha iLanzhi Institute of Biology
Ukuze kugqugquzelwe futhi kube nomthelela ekuthuthukisweni kwemboni yemfuyo ekhaya naphesheya, i-Xuzhou Animal Nutrition Institute, uHulumeni Wesifunda SaseTongshan, iSichuan Agricultural University kanye neJiangsu Sustar, izinhlangothi ezine zasungula iXuzhou Lianzhi Biotechnology Research Institute ngoDisemba 2019.
USolwazi u-Yu Bing we-Animal Nutrition Research Institute yaseSichuan Agricultural University usebenze njengomfundisi, uSolwazi Zheng Ping kanye noProfessor Tong Gaogao wasebenza njengephini likathishanhloko. Osolwazi abaningi be-Animal Nutrition Research Institute yaseSichuan Agricultural University basize ithimba lochwepheshe ukuba lisheshise ukuguqulwa kwempumelelo yesayensi nezobuchwepheshe embonini yokufuywa kwezilwane futhi likhuthaze ukuthuthukiswa kwemboni.
Njengelungu LeKomidi Likazwelonke Lobuchwepheshe Lokumiswa Kwemboni Yokuphakelayo futhi eliwine Umklomelo Wokunikela Ngezinto Ezivamile wase-China, u-Sustar ubambe iqhaza ekubhaleni noma ekubuyekezeni amazinga angu-13 emikhiqizo kazwelonke noma yezimboni kanye nenqubo engu-1 kusukela ngo-1997.
U-Sustar uphumelele isitifiketi sohlelo lwe-ISO9001 kanye ne-ISO22000 yomkhiqizo womkhiqizo we-FAMI-QS, wathola amalungelo obunikazi okusungulwa okungu-2, amamodeli angu-13 amamodeli asetshenziswayo, wamukela amalungelo obunikazi angama-60, futhi waphumelela "Ukumiswa okujwayelekile kohlelo lokuphathwa kwempahla yengqondo", futhi kwaqashelwa njengebhizinisi elisha lobuchwepheshe obusezingeni likazwelonke.
Ulayini wethu wokukhiqiza okuphakelayo okuxubile kanye nemishini yokomisa isendaweni ehamba phambili embonini. I-Sustar ine-chromatograph ewuketshezi esebenza kahle, i-spectrophotometer yokumuncwa kwe-athomu, i-ultraviolet ne-spectrophotometer ebonakalayo, i-atomic fluorescence spectrophotometer namanye amathuluzi okuhlola amakhulu, ukucushwa okuphelele nokuthuthukile.
Sinochwepheshe bezilwane abangaphezu kuka-30, odokotela bezilwane, abahlaziyi bamakhemikhali, onjiniyela bemishini kanye nochwepheshe abakhulu ekucutshungulweni kokuphakelayo, ucwaningo nokuthuthukiswa, ukuhlolwa kwaselabhorethri, ukuhlinzeka amakhasimende ngohlu olugcwele lwezinsizakalo kusukela ekuthuthukisweni kwefomula, ukukhiqizwa komkhiqizo, ukuhlolwa, ukuhlolwa, ukuhlanganiswa kohlelo lomkhiqizo nokusetshenziswa nokunye.
Ukuhlolwa kwekhwalithi
Sihlinzeka ngemibiko yokuhlola yeqoqo ngalinye lemikhiqizo yethu, njengezinsimbi ezisindayo nezinsalela zamagciwane. Iqoqo ngalinye lama-dioxin kanye ne-PCBS lithobela izindinganiso ze-EU. Ukuqinisekisa ukuphepha nokuhambisana.
Siza amakhasimende ukuthi aqedelele ukuthotshelwa kokulawula kwezithasiselo zokuphakelayo emazweni ahlukene, njengokubhaliswa nokugcwalisa e-EU, USA, South America, Middle East nakwezinye izimakethe.
Amandla Okukhiqiza
Amandla okukhiqiza umkhiqizo oyinhloko
I-Copper sulfate - amathani ayi-15,000 / ngonyaka
TBCC -6,000 amathani/ngonyaka
I-TBZC -6,000 amathani / ngonyaka
I-potassium chloride - amathani ayi-7,000 / ngonyaka
Uchungechunge lwe-Glycine chelate - amathani ayi-7,000 / ngonyaka
Uchungechunge oluncane lwe-peptide chelate-3,000 amathani / ngonyaka
I-Manganese sulfate - amathani angama-20,000 / ngonyaka
I-Ferrous sulfate - amathani angama-20,000 / ngonyaka
I-Zinc sulfate - amathani angama-20,000 / ngonyaka
I-Premix (Amavithamini/Amaminerali)-60,000 amathani/ngonyaka
Umlando weminyaka engaphezu kwengama-35 enefektri emihlanu
Iqembu le-Sustar linamafekthri amahlanu e-China, anamandla onyaka afinyelela kumathani angu-200,000, ahlanganisa ngokuphelele amamitha-skwele angama-34,473, abasebenzi abangama-220. Futhi siyinkampani eqinisekisiwe ye-FAMI-QS/ISO/GMP.
Amasevisi Enziwe ngokwezifiso
Yenza ngokwezifiso Izinga Lokuhlanzeka
Inkampani yethu inenani lemikhiqizo enamazinga ahlukene okuhlanzeka, ikakhulukazi ukusekela amakhasimende ethu ukwenza izinsizakalo ezenziwe ngokwezifiso, ngokuya ngezidingo zakho. Isibonelo, umkhiqizo wethu i-DMPT itholakala ku-98%, 80%, kanye nezinketho zokuhlanzeka ezingu-40%; I-Chromium picolinate ingahlinzekwa nge-Cr 2% -12%; futhi i-L-selenomethionine ingahlinzekwa nge-Se 0.4% -5%.
Ukupakisha Ngokwezifiso
Ngokwezidingo zakho zokuklama, ungenza ngezifiso ilogo, usayizi, umumo, kanye nephethini yokupakishwa kwangaphandle
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